Atorvastatin in Pregnancy

Case

I used atorvastatin 10 mg daily, first two weeks of pregnancy

Report

Atorvastatin is a medication that belongs to the class of drugs known as statins, or HMG-CoA reductase inhibitors. It is commonly prescribed to manage hypercholesterolemia and reduce the risk of cardiovascular events by lowering cholesterol levels. The standard dosage can vary, but it often starts at 10 mg once daily, with adjustments based on the patient's response and medical condition.

In terms of teratogenicity, atorvastatin is classified as Pregnancy Category X, meaning it is contraindicated during pregnancy due to potential risks to the fetus. Although there are no adequate and well-controlled studies in pregnant women, animal studies and some case reports suggest that exposure to statins may be associated with adverse fetal outcomes. These may include structural defects, intrauterine growth restriction (IUGR), and fetal death. However, in the case of atorvastatin, specific data on human teratogenicity is limited. The risks are considered significant enough that atorvastatin use is typically avoided during pregnancy.

Given that atorvastatin is contraindicated during pregnancy, you should discontinue its use immediately and consult your healthcare provider for further evaluation and guidance. The potential risk to the fetus necessitates careful monitoring and consideration of alternative treatments.

[This report] offers an AI-assisted literature review service on the potential teratogenic effects of medications. The information provided is for general reference only, and we do not accept responsibility for its accuracy or completeness. By using this service, users agree to these terms. For more detailed information and personalized advice, please consult a healthcare professional.